Mechanistic insights into the therapeutic potential of Angiotensin type 2 receptors (AT2R) in shaping behavior of astrocytes and microglia during hypertensive state

Journal article

S. Bhat
Alzheimer's & Dementia, 2023

Cite

APA Click to copy
Bhat, S. (2023). Mechanistic insights into the therapeutic potential of Angiotensin type 2 receptors (AT2R) in shaping behavior of astrocytes and microglia during hypertensive state. Alzheimer's &Amp;Amp; Dementia.

Chicago/Turabian Click to copy
Bhat, S. “Mechanistic Insights into the Therapeutic Potential of Angiotensin Type 2 Receptors (AT2R) in Shaping Behavior of Astrocytes and Microglia during Hypertensive State.” Alzheimer's & Dementia (2023).

MLA Click to copy
Bhat, S. “Mechanistic Insights into the Therapeutic Potential of Angiotensin Type 2 Receptors (AT2R) in Shaping Behavior of Astrocytes and Microglia during Hypertensive State.” Alzheimer's &Amp;Amp; Dementia, 2023.

BibTeX Click to copy

@article{s2023a,
  title = {Mechanistic insights into the therapeutic potential of Angiotensin type 2 receptors (AT2R) in shaping behavior of astrocytes and microglia during hypertensive state},
  year = {2023},
  journal = {Alzheimer's &amp; Dementia},
  author = {Bhat, S.}
}

Abstract

Astrocytes are the major glial cell type in the central nervous system (CNS) and play a critical role in the pathogenesis of neuroinflammatory and neurodegenerative diseases. In particular, astrocytic activation during neuroinflammatory conditions perpetuates the inflammatory response and brain damage and neurodegeneration. Conversely, Angiotensin type 2 receptor (AT2R) activation is known to promote neuroprotection.